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PAR-2 (6-1) amide (human)

Name
PAR-2 (6-1) amide (human)
Molecular structural formula
Purity
95%
CAS Number
942413-05-0
Formula
C28H54N8O7
MW
614.78
Target
Protease Activated Receptor (PAR)
Sequence
Val-Lys-Gly-Ile-Leu-Ser-NH2
Sequence Shortening
VKGILS-NH2
InChIKey
IYJUKRSADJIIBX-WAUHAFJUSA-N
Solubility in water
100 mg/mL
References
[1].M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131(4):689-94. [2].David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1441-9.
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Product details
Data download

VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells.