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Synthesis of unnatural amino acids and other blocks

PACAP(6-27) (human, chicken, mouse, ovine, porcine, rat)

Name
PACAP(6-27) (human, chicken, mouse, ovine, porcine, rat)
Molecular structural formula
Purity
≥95%
CAS Number
136134-68-4
Formula
C121H193N33O30S
MW
2638.15
Target
Adenylate Cyclase
Sequence
Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
Sequence Shortening
FTDSYSRYRKQMAVKKYLAAVL-NH2
References
[1]. Gaspo R, et al. Canine adrenal catecholamine response to VIP is blocked by PACAP-(6-27) in vivo. Am J Physiol. 1997 May;272(5 Pt 2):R1606-12.
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PACAP (6-27) (human, ovine, rat) is a PACAP receptor antagonist that blocks the canine adrenal catecholamine response to exogenous vasoactive intestinal peptide (VIP). PACAP (6-27) (human, ovine, rat) has the potential to study cardiovascular and neurological diseases.