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Home / Peptide products / Catalog peptides / O (773 species) / Orexin /
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Orexin B, rat, mouse

Name
Orexin B, rat, mouse
Molecular structural formula
Purity
≥95%
CAS Number
202801-92-1
Formula
C126H215N45O34S
MW
2936.46
Target
Orexin Receptor (OX Receptor)
Sequence
Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg- Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Sequence Shortening
RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
InChIKey
RLVZFBVFVIDDPQ-GWQFQBPDSA-N
Solubility in water
16.67mg/mL
References
[1]. Smart D, et al. Orexins: a new family of neuropeptides. Br J Anaesth. 1999 Nov;83(5):695-7. [2]. Sakurai T, et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998 Feb 20;92(4):573-85. [3]. Ziolkowska A, et al. Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells. Int J Mol Med. 2008;22(6):749-755. [4]. Zhang G, et al. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Neuropharmacology. 2018;133:38-50.
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Product details
Data download

Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.