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Oligopeptide-68

Name
Oligopeptide-68
Molecular structural formula
Purity
≥95%
CAS Number
1206525-47-4
Formula
C62H91N17O21
MW
1410.49
Target
others
Sequence
Gly-Arg-Gly-Asp-Tyr-Ile-Trp-Ser-Leu-Asp-Thr-Gln
Sequence Shortening
GRGDYIWSLDTQ
InChIKey
HPPYJXKCLMBZCN-ZDQKBINTSA-N
Solubility in DMSO
25 mg/mL
References
[1]. Pratchyapurit WO. Combined use of two formulations containing diacetyl boldine, TGF-β1 biomimetic oligopeptide-68 with other hypopigmenting/exfoliating agents and sunscreen provides effective and convenient treatment for facial melasma. Either is equal to or is better than 4% hydroquinone on normal skin. J Cosmet Dermatol. 2016;15(2):131-144.
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Product details
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Oligopeptide-68 is a whitening peptide containing twelve amino acids. It inhibits the MITF molecular channel by simulating the binding of TGF-β to cell receptors, reduces pigmentation, and then reduces the production of melanin, making the skin brighter. In addition, it can inhibit the activity of tyrosine protease, prevent the formation of melanin, and reduce the excessive production of melanin by inhibiting MSH.