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Synthesis of unnatural amino acids and other blocks

Oligopeptide-68

Name
Oligopeptide-68
Molecular structural formula
Purity
95%
CAS Number
1206525-47-4
Formula
C62H91N17O21
MW
1410.49
Target
others
Sequence
Gly-Arg-Gly-Asp-Tyr-Ile-Trp-Ser-Leu-Asp-Thr-Gln
Sequence Shortening
GRGDYIWSLDTQ
Solubility in DMSO
25 mg/mL
References
[1]. Pratchyapurit WO. Combined use of two formulations containing diacetyl boldine, TGF-β1 biomimetic oligopeptide-68 with other hypopigmenting/exfoliating agents and sunscreen provides effective and convenient treatment for facial melasma. Either is equal to or is better than 4% hydroquinone on normal skin. J Cosmet Dermatol. 2016;15(2):131-144.
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Oligopeptide-68 reduces melanin production by inhibiting MSH (melanin) and stops melanin overproduction.