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Synthesis of unnatural amino acids and other blocks

Obestatin, rat, mouse

Name
Obestatin, rat, mouse
Molecular structural formula
Purity
≥95%
CAS Number
869705-22-6
Formula
C114H174N34O31
MW
2516.87
Target
GHSR
Sequence
Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2
Sequence Shortening
FNAPFDVGIKLSGAQYQQHGRAL-NH2
InChIKey
FNAPFDVGIKLSGAQYQQHGRAL-NH2
References
[1]. Azadeh Toosi, et al. Obestatin Improve Spatial Memory Impairment in a Rat Model of Fetal Alcohol Spectrum Disorders via Inhibiting Apoptosis and Neuroinflammation. Neuropeptides. 2019 Apr;74:88-94. [2]. Science. 2005 Nov 11;310(5750):996-9. doi: 10.1126/science.1117255.
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Product details
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Obestatin(rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. Obestatin(rat) suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin(rat) has anti-inflammatory, anti-myocardial infarction and antioxidant activities.