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Neuro Peptide Y(13-36)(porcine)

Name
Neuro Peptide Y(13-36)(porcine)
Molecular structural formula
Purity
95%
CAS Number
367518-31-8
Formula
C135H209N41O36
MW
2982.36
Target
Neuropeptide Y Receptor
Sequence
Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence Shortening
PAEDLARYYSALRHYINLITRQRY-NH2
InChIKey
HEALDAASUSTTPJ-QGTLAHJGSA-N
References
[1]. [Leu31-Pro34] neuropeptide Y identifies a subtype of 125I-labeled peptide YY binding sites in the rat brain. [2]. Centrally truncated and stabilized porcine neuropeptide Y analogs: design, synthesis, and mouse brain receptor binding. [3]. Effects of galanin message-associated peptide and neuropeptide Y against various non-albicans Candida strains.
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Neuropeptide Y 13-36 (porcine) is a selective neuropeptide Y2 receptor agonist (Ki = 0.18 nM). It mimics the effects of NPY at presynaptic receptors in vas deferens.

This fragment is able to compete with the intact NPY for essentially all binding sites in rat brain. However, it is less potent than the native peptide in its NPY-receptor binding affinity.