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Nafarelin

Name
Nafarelin
Molecular structural formula
Purity
≥98%
CAS Number
76932-56-4
Formula
C66H83N17O13
MW
1322.49
Sequence
Pyr-His-Trp-Ser-Tyr-D-2-Nal-Leu-Arg-Pro-Gly-NH2
Sequence Shortening
{Pyr}-HWSY{-D-2-Nal}-LRPG-NH2
InChIKey
RWHUEXWOYVBUCI-ITQXDASVSA-N
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Narfarelin is used to treat endometriosis, inflammation, and cysts, and its effect is mainly by inhibiting the hypothalamic-pituitary-ovarian axis, resulting in a low estrogen state in the body, causing ectopic endometrial atrophy. In addition, nafarelin can also be used to treat central precocious puberty. Endometriosis is an estrogen-dependent condition in which ovarian hormones are required for ectopic endometrial growth.