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Synthesis of unnatural amino acids and other blocks

MC-Val-Cit-PAB-NH-C2-NH-Boc

Name
MC-Val-Cit-PAB-NH-C2-NH-Boc
Molecular structural formula
Purity
≥95%
CAS Number
1616727-22-0
Formula
C36H54N8O10
MW
758.86
Target
ADC Linker
InChIKey
NBIUDKXQNRHCFG-YZNIXAGQSA-N
References
[1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.
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MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).