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Synthesis of unnatural amino acids and other blocks

MC-GGFG-Glycolic acid

Name
MC-GGFG-Glycolic acid
Molecular structural formula
Purity
≥95%
CAS Number
1599440-25-1
Formula
C28H36N6O10
MW
616.62
Target
ADC Linker
Sequence
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Sequence Shortening
MC-GGFG-NH-CH2-O-CH2COOH
InChIKey
SODPQQOBNODMSG-FQEVSTJZSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Masuda, Takeshi, et al. Conjugué anticorps-médicament. WO2014057687A1.
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Product details
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)