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Synthesis of unnatural amino acids and other blocks

MBP (87-99), human; Myelin Basic Protein (87-99), guinea pig, human

Name
MBP (87-99), human; Myelin Basic Protein (87-99), guinea pig, human
Molecular structural formula
Purity
≥95%
CAS Number
118506-26-6
Formula
C74H114N20O17
MW
1555.86
Target
others
Sequence
Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro
Sequence Shortening
VHFFKNIVTPRTP
InChIKey
XSSZRUKIAIQNAZ-SAKFXWCOSA-N
References
[1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12. [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J M.
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Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS).