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LHRH-Ⅲ, lamprey

Name
LHRH-Ⅲ, lamprey
Molecular structural formula
Purity
≥95%
CAS Number
147859-97-0
Formula
C59H75N18O14
MW
1259.4
Target
GnRH Receptor
Sequence
Pyr-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2
Sequence Shortening
{Pyr}-HWSHDWKPG-NH2
InChIKey
RTASYRSYWSLWJV-CSYZDTNESA-N
Solubility in water
50mg/mL
References
[1]. Pappa EV, et al. Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies. Biopolymers. 2012;98(6):525-34. [2]. Manea M, et al. lGnRH-III -- a promising candidate for anticancer drug development. Protein Pept Lett. 2013 Apr;20(4):439-49.
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LGnRH-III, lamprey, an isoform of GnRH isolated from the sea lamprey, is a weak GnRH agonist with antitumor activities.