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Synthesis of unnatural amino acids and other blocks

Histone H3 (1 - 25),amide

Name
Histone H3 (1 - 25),amide
Molecular structural formula
Purity
≥95%
CAS Number
1373320-65-0
Formula
C110H202N42O32
MW
2625.1
Target
others
Sequence
Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala--NH2
Sequence Shortening
ARTKQTARKSTGGKAPRKQLATKAA-NH2
InChIKey
YNLQDZAEUXMPIO-FZRLICTESA-N
References
[1]. Kumar M, et al. Biochemical Assay Development for Histone Methyltransferases Using a Transcreener-Based Assay for S-Adenosylhomocysteine. Assay Drug Dev Technol. 2015;13(4):200-209.
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Histone H3 (1-25), amide is an N-terminal peptide fragment of histone H3. Histone H3 (1-25), amide can be used to identify the substrate for histone methyltransferases (HMTs). Histone H3 (1-25), amide, as a substrate for HMT G9a, shows more efficient than histone H3 (15-39) and full-length histone H3.