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Synthesis of unnatural amino acids and other blocks

HIV-gp120-Fragment (318-327)

Name
HIV-gp120-Fragment (318-327)
Molecular structural formula
Purity
≥95%
CAS Number
147841-68-7
Formula
C48H80N16O12
MW
1073.27
Target
HIV
Sequence
Arg-Gly-Pro-Gly-Arg-Ala-Phe-Val-Thr-Ile
Sequence Shortening
RGPGRAFVTI
InChIKey
OPTVPTKXPSEPBD-JLHVISHLSA-N
References
[1] Y.Nakagawa et al., Immunology, 101, 76(2000).
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The decapeptide RGPGRAFVTI, derived from the V3 loop region of HIV-1 type IIIB gp120, efficiently induced HIV-1 env-specific cytotoxic T lymphocyte activity in mice (no carrier needed).