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HIV-1 gag Protein p24 (65-73) (isolates MAL/U455)

Name
HIV-1 gag Protein p24 (65-73) (isolates MAL/U455)
Molecular structural formula
Purity
≥95%
CAS Number
334731-59-8
Formula
C44H79N11O14S2
MW
1050.31
Target
HIV
Sequence
Ala-Met-Gln-Met-Leu-Lys-Asp-Thr-Ile
Sequence Shortening
AMQMLKDTI
InChIKey
VPOLJMZMAKOJCW-UHFFFAOYSA-N
References
[1].Bianchi E, Finotto M, Ingallinella P, Hrin R, Carella AV, Hou XS, Schleif WA, Miller MD, Geleziunas R, Pessi A (2005). Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection. PNAS., 102(36):12903-12908 [2].de Rosny E, Vassell R, Jiang S, Kunert R, Weiss CD (2004). Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes. J. Virol., 78(5):2627-2631. [3]. Klostermeier D, Bayer P, Kraft M, Frank RW, Rösch P (1997). Spectroscopic investigations of HIV-1 trans-activator and related peptides in aqueous solutions. Biophysical Chemistry, 63(2):87-96. [4].Ho DD, Kaplan JC, Rackauskas IE, Gurney ME (1988). Second conserved domain of gp120 is important for HIV infectivity and antibody neutralization. Science, 239(4843):1021-1023.
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Human immunodeficiency virus (HIV) is a lentivirus that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. Over 5000 HIV-related peptides have been synthesized, that inhibit different stages of viral life cycle.