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Synthesis of unnatural amino acids and other blocks

Glutathione

Name
Glutathione
Molecular structural formula
Purity
95%
CAS Number
70-18-8
Formula
C10H17N3O6S
MW
307.32
Target
Endogenous Metabolite,Reactive Oxygen Species,Ferroptosis
Sequence
γGlu-Cys-Gly
Sequence Shortening
γGlu-CG
InChIKey
RWSXRVCMGQZWBV-WDSKDSINSA-N
Solubility in water
62.5 mg/mL
References
[1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.
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As an important antioxidant in the body, glutathione can scavenge free radicals in the human body; Because GSH itself is susceptible to oxidation by certain substances, it can protect the sulfhydryl groups in many proteins and enzymes from being oxidized by harmful substances in the body, so as to ensure the normal physiological functions of proteins and enzymes. There is a lot of glutathione in human red blood cells, which is of great significance to protect the sulfhydryl groups of proteins on the red blood cell membrane in a reduced state and prevent hemolysis.