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Gastrin Tetrapeptide

Name
Gastrin Tetrapeptide
Molecular structural formula
Purity
≥95%
CAS Number
1947-37-1
Formula
C29H36N6O6S
MW
596.71
Target
Cholecystokinin Receptor
Sequence
Trp-Met-Asp-Phe-NH2
Sequence Shortening
WMDF-NH2
InChIKey
RGYLYUZOGHTBRF-BIHRQFPBSA-N
Solubility in DMSO
8.33 mg/mL
References
[1]. M Tatsuta, et al. Effect of 6-hydroxydopamine on gastric carcinogenesis and tetragastrin inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. Cancer Res. 1989 Aug 1;49(15):4199-203. [2]. Nathalie Lara, et al. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology. 2003 Oct;28(10):1840-5. [3]. Y Komuro,et al. Effects of tetragastrin on mucus glycoprotein in rat gastric mucosal protection. Gastroenterol Jpn. 1992 Oct;27(5):597-603. [4]. A A Karelin,et al. Tetragastrin activation of rat gastric mucosa adenyl cyclase in vitro. Biull Eksp Biol Med. 1981 Apr;91(4):440-1.
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Product details
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Tetragastrin (Cholecystokinin tetrapeptide; CCK-4) is the C-terminal tetrapeptide of gastrin. Tetragastrin can stimulate gastric secretion. Tetragastrin is a Cholecystokinin (CCK-4) receptor agonis. Gastric mucosal protection.