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Gastrin-1, human ( Gastrin17)

Name
Gastrin-1, human ( Gastrin17)
Molecular structural formula
Purity
≥95%
CAS Number
10047-33-3
Formula
C97H125N20O31S
MW
2098.22
Target
Cholecystokinin Receptor
Sequence
Pyr-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2
Sequence Shortening
{Pyr-Glu}-GPWLEEEEEAYGWMDF-NH2
InChIKey
GKDWRERMBNGKCZ-RNXBIMIWSA-N
References
[1]. Noble F, et al. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev. 1999 Dec;51(4):745-81. [2]. Blandizzi C, et al. CCK1 and CCK2 receptors regulate gastric pepsinogen secretion. Eur J Pharmacol. 1999 May 28;373(1):71-84.
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Gastrin I, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor.