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GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)

Name
GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)
Molecular structural formula
Purity
≥95%
CAS Number
161748-29-4
Formula
C140H214N36O43
MW
3089.48
Target
GCCR
Sequence
Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
Sequence Shortening
EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
InChIKey
WPNGPBPCQMDAAD-WRFZDFFOSA-N
Solubility in water
≥ 25 mg/mL
References
[1]. Knudsen LB, et al. Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur J Pharmacol. 1996;318(2-3):429-435. [2]. Elahi D, et al. GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity (Silver Spring). 2008;16(7):1501-1509.
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Product details
Data download

GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor.