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FITC-LC-TAT (47-57)

Name
FITC-LC-TAT (47-57)
Molecular structural formula
Purity
95%
Formula
C91H141N35O19S1
MW
2061.38
Target
HIV
Sequence
5FITC-Ahx-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2
Sequence Shortening
5FITC-Ahx-YGRKKRRQRRR-NH2
InChIKey
LGQQNQDWKGOXHB-KJJQCGMTSA-N
References
[1]. Gopikrishna Moku, et al. Improving Payload Capacity and Anti-Tumor Efficacy of Mesenchymal Stem Cells Using TAT Peptide Functionalized Polymeric Nanoparticles. Cancers (Basel). 2019 Apr 6;11(4):491. [2]. Ziegler A, et al. Interaction of the protein transduction domain of HIV-1 TAT with heparan sulfate: binding mechanism and thermodynamic parameters. Biophys J. 2004 Jan;86(1 Pt 1):254-63.
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This fluorescent (FITC)-labeled TAT peptide contains a long chain (LC) to prevent FITC from degradation. Abs/Em = 493/522 nm. TAT is the most characteristic fragment of HIV trans-activator protein (TAT). The arginine-rich TAT peptide penetrates the plasma membrane directly rather than through endocytosis.