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Enfuvirtide(T-20)

Name
Enfuvirtide(T-20)
Molecular structural formula
Purity
≥95%
CAS Number
159519-65-0
Formula
C204H301N51O64
MW
4462
Target
HIV
Sequence
Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
Sequence Shortening
Ac-YTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWF-NH2
Solubility in DMSO
20 mg/mL
Solubility in water
0.67 mg/mL
References
[1]. Figueira TN, et al. Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance. Sci Rep. 2017 Mar 30;7:45647. [2]. Cao P, et al. The improved efficacy of Sifuvirtide compared with Enfuvirtide might be related to its selectivity for the rigid biomembrane, as determined through surface plasmon resonance. PLoS One. 2017 Feb 16;12(2):e0171567. [3]. Wang X, et al. IFN-λ Inhibits Drug-Resistant HIV Infection of Macrophages. Front Immunol. 2017 Mar 6;8:210.
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Product details
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Enfuvirtide (T20;DP178) is an anti-HIV-1 fusion inhibitor peptide.