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Synthesis of unnatural amino acids and other blocks

Elcatonin

Name
Elcatonin
Molecular structural formula
Purity
≥98%
CAS Number
60731-46-6
Formula
C148H244N42O47
MW
3363.77
Sequence
Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2 (Ser1-Asu Lacton)
Sequence Shortening
SNLST(Asu)VLGKLSQELHKLQTYPRTDVGAGTP-NH2(Ser1-Asu Lacton)
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Elcatonin is a synthetic eel calcitonin analog that can inhibit the activity of osteoclasts, reduce bone resorption, prevent bone calcium loss, and thus lower blood calcium levels. Its calcium-lowering effect is 10 to 40 times that of human calcitonin.