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Synthesis of unnatural amino acids and other blocks

EMCS

Name
EMCS
Molecular structural formula
Purity
≥95%
CAS Number
55750-63-5
MW
C14H16N2O6
MOLFile
308.29
Target
ADC Linker
InChIKey
VLARLSIGSPVYHX-UHFFFAOYSA-N
Solubility in DMSO
230 mg/mL
References
[1]. Shinya Kida, et al. Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters. Chem Pharm Bull (Tokyo). 2007 Apr;55(4):685-7. [2]. Shinya Kida, et al. Evaluation of synthetic cell-penetrating peptides, Pro-rich peptide and octaargine derivatives, as adenovirus vector carrier. Protein Pept Lett. 2010 Feb;17(2):164-7.
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6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates.