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Decapeptide-12

Name
Decapeptide-12
Molecular structural formula
Purity
≥95%
CAS Number
137665-91-9
Formula
C65H90N18O17
MW
1395.55
Target
Tyrosinase; Sirtuin
Sequence
Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr
Sequence Shortening
YRSRKYSSWY
InChIKey
OYVFAMLECFSFEI-UHFFFAOYSA-N
References
[1]. Anan Abu Ubeid, et al. Short-sequence oligopeptides with inhibitory activity against mushroom and human tyrosinase. J Invest Dermatol. 2009 Sep;129(9):2242-9. [2]. Akihito Ochiai, et al. New tyrosinase inhibitory decapeptide: Molecular insights into the role of tyrosine residues. J Biosci Bioeng. 2016 Jun;121(6):607-613. [3]. Basil M H, et al. Tyrosinase inhibitors with potent anti-senescence activity in human neonatal keratinocyte progenitors. J Dermatol Surg Res Ther, 2019, 2019: 30-39.
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Product details
Data download

Decapeptide-12 is a cosmetic ingredient that effectively inhibits tyrosinase activity, reduces melanin production, and has a whitening effect. It can lighten a variety of spots, such as melasma, freckles, age spots, and sun spots, while improving uneven skin tone and photodamage.

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Decapeptide-12 COA
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Decapeptide-12 HPLC
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Decapeptide-12 MS