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Synthesis of unnatural amino acids and other blocks

DBCO-C3-Acid

Name
DBCO-C3-Acid
Molecular structural formula
Purity
≥95%
CAS Number
1207355-31-4
Formula
C20H17NO3
MW
319.35
Target
ADC Linker
InChIKey
KDYPHAQTQRXDCD-UHFFFAOYSA-N
Solubility in DMSO
100 mg/mL
References
[1]. van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26(11):2233-2242.
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DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker.