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Chlorotoxin

Name
Chlorotoxin
Molecular structural formula
Purity
95%
CAS Number
163515-35-3
Formula
C158H249N53O47S11
MW
3995.71
Target
Chloride Channel
Sequence
Met-Cys-Met-Pro-Cys-Phe-Thr-Thr-Asp-His-Gln-Met-Ala-Arg-Lys-Cys-Asp-Asp-Cys-Cys-Gly-Gly-Lys-Gly-Arg-Gly-Lys-Cys-Tyr-Gly-Pro-Gln-Cys-Leu-Cys-Arg-NH2(Disulfide Bridge:Cys2-Cys19 & Cys5-Cys28 & Cys16-Cys33 & Cys20-Cys35)
Sequence Shortening
MCMPCFTTDHQMARKCDDCCGGKGRGKCYGPQCLCR-NH2(Disulfide Bridge:C2-C19 & C5-C28 & C16-C33 & C20-C35)
InChIKey
QPAKKWCQMHUHNI-UHFFFAOYSA-N
References
[1].Chlorotoxin: Structure, activity, and potential uses in cancer therapy. [2]. Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion.
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Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.