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Cetrorelix

Name
Cetrorelix
Molecular structural formula
Purity
≥98%
CAS Number
120287-85-6
Formula
C70H92ClN17O14
MW
1431.04
Target
GnRH Receptor
Sequence
Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2
Sequence Shortening
Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-SY-D-Cit-LRPa-NH2
InChIKey
SBNPWPIBESPSIF-MHWMIDJBSA-N
References
[1]. Diedrich K, et al. Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation. Hum Reprod. 1994 May;9(5):788-91. [2]. Meirow D, et al. The GnRH antagonist cetrorelix reduces cyclophosphamide-induced ovarian follicular destruction in mice. Hum Reprod. 2004 Jun;19(6):1294-9.
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Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice.