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Synthesis of unnatural amino acids and other blocks

Calcitonin, eel

Name
Calcitonin, eel
Molecular structural formula
Purity
≥95%
CAS Number
57014-02-5
Formula
C146H241N43O47S2
MW
3414.94
Target
others
Sequence
Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser- Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val- Gly-Ala-Gly-Thr-Pro-NH2(Disulfide bridge:Cys1-Cys7)
Sequence Shortening
CSNLSTCVLGKLSQELHKLQTYPRTDVGAGTP-NH2 (Disulfide bridge: Cys1-Cys7)
InChIKey
JDJALSWDQPEHEJ-UHFFFAOYSA-N
References
[1]. Sortino MA, et al. Comparative effects of eel calcitonin, salmon calcitonin and [Asu1,7]eel calcitonin on hypophyseal and osteoblastic function. Gynecol Endocrinol. 1993 Jun;7(2):89-96.
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Calcitonin, eel is the thyroid hormone peptide that contributes to the regulation of calcium homeostasis, widely used in the research of postmenopausal osteoporosis.