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Calcitonin (salmon)

Name
Calcitonin (salmon)
Molecular structural formula
Purity
≥98%
CAS Number
47931-85-1
Formula
C145H240N44O48S2
MW
3431.85
Target
CGRP Receptor
Sequence
Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-T hr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bridge: Cys1-Cys7)
Sequence Shortening
CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP-NH2 (Disulfide bridge: Cys1-Cys7)
InChIKey
IYTKRMFJECGBRF-LXQLIYPUSA-N
Solubility in DMSO
50 mg/mL
Solubility in water
100 mg/mL
References
[1]. Feigh M, et al. Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats. Br J Pharmacol. 2012 Sep;167(1):151-63.
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Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption.