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Big Endothelin-1 (1-38), human

Name
Big Endothelin-1 (1-38), human
Molecular structural formula
Purity
≥95%
CAS Number
120796-97-6
Formula
C189H282N48O56S5
MW
4282.96
Target
Vasopressin Receptor
Sequence
Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr- Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser(Disulfide bridge:Cys1-Cys15, Cys3-Cys11)
Sequence Shortening
CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)
References
[1]. Marie-Hélène Fecteau, et al. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension. 2005 Jul;46(1):87-92.
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Product details
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Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide.