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BCR-ABL fusion protein (b3a2)-HLA DR4

Name
BCR-ABL fusion protein (b3a2)-HLA DR4
Molecular structural formula
Normal/Tumor
chronic myeloid leukemia
chronic myeloid leukemia
HLA
DR4(用于人类白细胞抗原 II类)
DR4(用于人类白细胞抗原 II类)
HLA%
24
24
Peptide Sequence
ATGFKQSSKALQRPVAS(其中"KALQRPVAS"为独特抗原突变所导致的修饰残基)
ATGFKQSSKALQRPVAS(其中"KALQRPVAS"为独特抗原突变所导致的修饰残基)
Position
920-936
Lymphocyte Stimulation
peptide
References
[1].Bosch GJ, Joosten AM, Kessler JH, Melief CJ, Leeksma OC. Recognition of BCR-ABL positive leukemic blasts by human CD4+ T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide. Blood. 1996 Nov 1, 88(9):3522-7. (PMID: 8896419)
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