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BAD (103-127) (human)

Name
BAD (103-127) (human)
Molecular structural formula
Purity
95%
CAS Number
331762-68-6
Formula
C158H222O45N42S1
MW
3461.77
Target
Bcl-2 Family
Sequence
5FAM-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Val-Asp-Ser-Phe-Lys-Lys
Sequence Shortening
5FAM-NLWAAQRYGRELRRMSDEFVDSFKK
InChIKey
NLSLFOGIVJOKDC-ZOKDAYPZSA-N
Solubility in water
≥ 50 mg/mL
References
[1].Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L). J Comput Aided Mol Des. 2011 May;25(5):413-26..
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Product details
Data download

BAD (103-127) (human), FAM-labeled is a FAM-labeled human BAD (103-127) (HY-P2468). BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL.