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Angiotensin III, human

Name
Angiotensin III, human
Molecular structural formula
Purity
≥95%
Price

1mg: $14.00

5mg: $42.00

10mg: $70.00

CAS Number
13602-53-4
Formula
C46H66N12O9
MW
931.1
Target
Angiotensin Receptor
Sequence
Arg-Val-Tyr-Ile-His-Pro-Phe
Sequence Shortening
RVYIHPF
InChIKey
QMMRCKSBBNJCMR-KMZPNFOHSA-N
Solubility in water
100mg/mL
References
[1]. Bosnyak S, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond). 2011 Oct;121(7):297-303. [2]. Kemp BA, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension. 2012 Aug;60(2):387-95. [3]. Gao J, et al. A new strategy for treating hypertension by blocking the activity of the brain renin-angiotensin system with aminopeptidase A inhibitors. Clin Sci (Lond). 2014 Aug;127(3):135-48.
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Product details
Data download

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT2R) agonist, with IC50s of 0.648 nM and 21.1 nM for AT2R and AT1R, respectively.