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Amyloid β-Protein (1-40)

Name
Amyloid β-Protein (1-40)
Molecular structural formula
Purity
95%
Formula
C194H295N53O58S1
MW
4329.8
Sequence
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Sequence Shortening
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
References
[1].Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures. [2]. Redox chemistry of copper-amyloid-beta: the generation of hydroxyl radical in the presence of ascorbate is linked to redox-potentials and aggregation state. [3]. Cerebrospinal fluid Abeta40 and Abeta42: natural course and clinical usefulness.
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β-Amyloid (1-40) TFA is a primary protein in plaques found in the brains of patients with Alzheimer's disease.