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Synthesis of unnatural amino acids and other blocks

Amylin (8-37),rat

Name
Amylin (8-37),rat
Molecular structural formula
Purity
≥95%
Price

1mg: $59.50

5mg: $182.00

10mg: $301.00

CAS Number
138398-61-5
Formula
C140H227N43O43
MW
3200.63
Target
Amylin Receptor
Sequence
Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
Sequence Shortening
ATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2
InChIKey
KXIRMGRGEHRNNC-ANJGTFPLSA-N
Solubility in water
50 mg/mL
References
[1]. Bower RL, et al. Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development. Br J Pharmacol. 2016 Jun;173(12):1883-98. [2]. Hettiarachchi M, et al. Rat amylin-(8-37) enhances insulin action and alters lipid metabolism in normal and insulin-resistant rats. Am J Physiol. 1997 Nov;273(5 Pt 1):E859-67.
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Product details
Data download

Amylin (8-37), rat is a truncated analog of native Amylin that selectively inhibits insulin-related glucose uptake and glycogen deposition in muscle tissue. Amylin (8-37), rat is a weak amylin receptor (AMY) antagonist.