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Synthesis of unnatural amino acids and other blocks

Amylin (1-13) (human)

Name
Amylin (1-13) (human)
Molecular structural formula
Purity
≥95%
Price

1mg: $35.00

5mg: $101.50

10mg: $168.00

CAS Number
198328-30-2
Formula
C54H95N19O19S2
MW
1378.6
Target
Amylin Receptor
Sequence
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala (Disulfide bridge:Cys2-Cys7)
Sequence Shortening
KCNTATCATQRLA (Disulfide bridge: Cys2-Cys7)
InChIKey
NUJHDVYKOOSMFN-UOJHWKIISA-N
References
[1]. Cao Q, et al. Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nat Struct Mol Biol. 2020 Jul;27(7):653-659.
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Product details
Data download

Amylin (1-13) (human) is a fragment and a residues within amyloid cores of Amylin (human IAPP). Amylin is a glucose-regulating hormone, deposits as amyloid fibrils in condition of type II diabetes (T2D). Amylin (1-13) (human) has no effect on firbl formation, as it cannot form fibrils by itself.