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Molecular structural formula
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Normal/Tumor
Melanoma
Melanoma
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HLA
DR1(用于人类白细胞抗原 II类)
DR1(用于人类白细胞抗原 II类)
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Peptide Sequence
YSVYFNLPADTIYTN
YSVYFNLPADTIYTN
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Lymphocyte Stimulation
autologous tumor cells
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NCBI Gene SummaryNCBI
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone development. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022].
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GeneCards Summary
BBX(BBX High Mobility Group Box Domain Containing) isa Protein Coding gene. Diseases associated with BBXinclude Hemophagocytic Lymphohistiocytosis,Familial, 3 and Hemolytic Disease Of Fetus AndNewborn, Rh-lnduced. An important paralog of thisgene is ClC.
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UniProtKB SwissProt Summary
Transcription factor that is necessary for cell cycle progression from G1 to S phase. (BBX_HUMAN,Q8WY36)
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References
[1].Wang HY, Peng G, Guo Z, Shevach EM, Wang RF. Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells. J Immunol. 2005 Mar 1, 174(5):2661-70. (PMID: 15728473).
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