Filters
Catalog peptides
Synthesis of unnatural amino acids and other blocks

(S)-16-amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic Acid

Name
(S)-16-amino-10-benzyl-6,9,12,15-tetraoxo-3-oxa-5,8,11,14-tetraazahexadecanoic Acid
Molecular structural formula
Purity
≥95%
CAS Number
1599440-20-6
Formula
C18H25N5O7
MW
423.43
Target
ADC Linker
Sequence
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Sequence Shortening
GGFG-NH-CH2-O-CH2COOH
InChIKey
JKVPATHZQGMASP-ZDUSSCGKSA-N
References
[1]. Masuda,et al. Preparation of antibody-drug conjugates for cancer therapy. World Intellectual Property Organization, WO2014057687 A1. 2014-04-17.
* All products on our website are for scientific research and cannot be used in human body
Product details
Data download

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate.