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Home / Peptide products / S (187 species) / Sarafotoxin / Sarafotoxin S6c
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Sarafotoxin S6c
Name
Sarafotoxin S6c
Molecular structural formula
Purity
≥95%
CAS Number
121695-87-2
Formula
C103H147N27O37S5
MW
2515.8
Target
Endothelin Receptor
Sequence
Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)Glu-Phe-Leu-Val-Lys-Glu-Val-Thr-Lys-Leu-Ile-Asp-Asn-Asn-Lys-Thr-Glu-Lys-Glu-Ile-Leu
Sequence Shortening
CTCNDMTDEECLNFCHQDVIW (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)
InChIKey
LXPHPKVWHQLBBA-UHFFFAOYSA-N
References
[1]. MacLean MR, et al. Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries. J Cardiovasc Pharmacol. 1995 Nov;26(5):822-30.
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Product details
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Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels.