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Catalog peptides
Synthesis of unnatural amino acids and other blocks
Angiopep-2-SH
Name
Angiopep-2-SH
Molecular structural formula
Purity
95%
CAS Number
906480-09-9
Formula
C107H154N30O32S1
MW
2404.61
Target
others
Sequence
Thr-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-Lys-Arg-Asn-Asn-Phe-Lys-Thr-Glu-Glu-Tyr-Cys
Sequence Shortening
TFFYGGSRGKRNNFKTEEYC
InChIKey
NTEVJSCQHIRPSH-UHFFFAOYSA-N
References
[1]. Kafa H, et al. Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo. J Control Release. 2016 Mar 10;225:217-29.
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Angiopep-2-cys is a conjugate of Angiopep-2 hydrochloride (HY-P2341) and cysteine. Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.