CRO
CDMO
CMO
Testing services
Scientific Customized Peptides
General linear peptide synthesis
Long peptide synthesis
Cyclic peptide synthesis (staple peptide)
Cyclic peptide synthesis (disulfide ring formation)
Stable isotope labeling peptide synthesis
Glycopeptides
Polypeptide modification
Peptide library synthesis
View all
Linker Synthesis Service
ADC Linker Synthesis Service
PDC Drug Synthesis Services
View all
FTE Services
PEPTIDE FTE
View all
Learn more
Popular peptides
Beauty peptides
Drug peptide intermediates and impurities
Cancer antigenic peptide
Catalog peptides
Linker
Synthesis of unnatural amino acids and other blocks
RGD,RAD Peptide
Ac-RADARADARADARADAYKKIIKKLRGDSP-NH2
Cell Adhesive Peptide [RGDC]
N-{Orn}-TA-c(RG-{DPhe}-K)
cyclo[RGDfK(Biotin)]
c{RGDfK(N3)}
Axltide
cyclo{RG-{DPhe}-K(Mpa)}
Fibronectin Adhesion-Promoting Peptide
View all
Targeted Peptide
Cys-Angiopep-2
Angiopep-2-SH
TfR Targeting Peptide、TfR-T12
Dcpep
GE11
G280-9
GPC3
c(RGD-DPhe-K)
View all
Peptide Tag
HA 12CA5 Epitope
Rhodopsin Epitope Tag
X-press
VSV-G Tag
V5 tag
Cys-T7 tag
T7 tag-Cys
T7 tag
View all
Learn more
Home / Peptide products / Amine Reactive Linker / SPDB
Filters
Popular peptides
RGD,RAD Peptide
Targeted Peptide
Peptide Tag
Cell-penetrating Peptides
Substrate Peptide
Inhibitor peptides
Amyloid β-Protein
Agonist Peptide
Beauty peptides
Anti-aging
Anti-inflammatory
Repair
Moisturizing
Whitening
Body care
Drug peptide intermediates and impurities
Neoplasm
Diabetes mellitus
Cardiovascular
Reproductive
Anti-infection
Osteoporosis
Other
Cancer antigenic peptide
Mutation
Differentiation
Overexpressed
Tumor-specific
Catalog peptides
Linker
ADC Linker
PDC Linker
RDC linker
PROTAC linker
Alkyne Reactive Linker
Amine Reactive Linker
Azide Reactive Linker
Click Reactive Linker
Thiol Reactive Linker
Linker Intermediate
Advanced Linker Intermediate
Synthesis of unnatural amino acids and other blocks
Fmoc protects unnatural amino acids
SPDB
Name
SPDB
Molecular structural formula
Purity
≥95%
CAS Number
115088-06-7
Formula
C13H14N2O4S2
MW
326.39
Target
ADC Linker
InChIKey
JSHOVKSMJRQOGY-UHFFFAOYSA-N
Solubility in DMSO
200 mg/mL
References
[1]. Widdison WC et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolitesin Cancer Cells andInduce High Levels of Bystander Killing. Bioconjug Chem, 2015 Nov 18, 26(11):2261-78.
* All products on our website are for scientific research and cannot be used in human body
Product details
Data download

SPDB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).