Home / Peptide products / Alkyne Reactive Linker / Propargyl-PEG2-CH2COOH
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Propargyl-PEG2-CH2COOH
Name
Propargyl-PEG2-CH2COOH
Molecular structural formula
Purity
≥95%
CAS Number
944561-46-0
Formula
C9H14O5
MW
202.2
Target
PROTAC Linkers
InChIKey
FWONAGPFSKACQC-UHFFFAOYSA-N
References
[1]. Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.
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Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propargyl-PEG2-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.