β-Endorphin (1-27), human Sequence:YGGFMTSEKSQTPLVTLFKNAIIKNAY Motifbiotech

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Home / Peptide products / E (116 species) / Endorphin / β-Endorphin (1-27), human

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β-Endorphin (1-27), human

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Name β-Endorphin (1-27), human	Molecular structural formula
Purity ≥95%
Formula C139H217N33O40S
MW 3022.54
Target Opioid Receptor
Sequence Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr
Sequence Shortening YGGFMTSEKSQTPLVTLFKNAIIKNAY
References [1]. Mansour A, et al. The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores. Brain Res. 1995 Nov 27;700(1-2):89-98. [2]. Nicolas P, et al. Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia. Proc Natl Acad Sci U S A. 1985 May;82(10):3178-81.

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β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia.