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Home / Peptide products / A (265 species) / Amylin / Amylin,human
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Amylin,human
Name
Amylin,human
Molecular structural formula
Purity
≥95%
CAS Number
122384-88-7
Formula
C165H261N51O55S2
MW
3903.4
Target
Amylin Receptor
Sequence
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2(Disulfide bridge:Cys2-Cys7)
Sequence Shortening
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2(Disulfide bridge:Cys2-Cys7)
InChIKey
PLOPBXQQPZYQFA-AXPWDRQUSA-N
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Product details
Data download

Endogenous peptide. Potent amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptor agonist. Potently inhibits insulin-stimulated glucose uptake in skeletal muscle cells (IC50 = 12 pM). Implicated in type II diabetes. Active in vivo. Rat (ab142399) and feline (ab142397) amylin also available.